Chapter 1 About

e-Campsis is a free web application developed by Calvagone that provides an intuitive and user-friendly interface for setting up population PK/PD simulations. The app is built on the R-package campsis, which serves as a powerful frontend for running model-based simulations using mrgsolve or rxode2.

1.1 e-Campsis versions

1.1.1 e-Campsis free

e-Campsis free is, as the name suggests, freely accessible to everyone without registration at

It comes with certain limitations regarding the size of the simulation and misses some functionality of the pro-version.

1.1.2 e-Campsis free+

If you want to simulate up to 16 arms or scenarios, 100 subjects/arm and 250 observations/arm we invite you to become an authorized user of e-Campsis free+.

Please send us the pre-filled email below and you will get an invitation to register as soon as possible:

1.1.3 e-Campsis pro

The professional version of e-Campsis is available as a yearly subscription and includes the following additional functionality:

  • Save/load e-campsis projects
  • NONMEM code import
  • Number of arms, scenarios, subjects, observations only limited by memory
  • Advanced customization of plots
  • NCA & summary statistics
  • Sensitivity analysis*
  • Forest plots*
  • Upload of external data for plotting*
  • Bootstrap covariates from external file or NHANES*
  • Replicate simulation with parameter uncertainty*
  • Import rxode2 and mrgsolve simulation code*
  • Personalized support via email

*Under development. Will be ready in Spring 2024.

For further information, contact us at the following e-mail address:

1.2 Application interface

The app consists of 4 main sections:

  • Model: a powerful model editor to edit your Campsis model online. Try out one of the numerous models available from the library and adapt it to your needs.
  • Trial design: an easy-to-use interface to quickly set-up the dosing regimen, observation times and covariates.
  • Simulation: a single screen dedicated to the simulation configuration and visualisation of the results. Explore different scenarios of parameter settings quickly and interactively.
  • Post-processing: here you can define summary variables such as non-compartmental PK parameters that you want to derive from your simulation results and show them in a table.
  • Download: last but not least, download the model, parameters and the whole code of the simulation to reproduce what you see in the app on your computer using the open-source package campsis.